Daniel L. Parton

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Research Experience

2012-pres Memorial Sloan Kettering Cancer Center
Postdoctoral Research Fellow, Computational Biology Center
Advisor: John D. Chodera
2011-2012 University of Chicago
Postdoctoral Scholar, Department of Chemistry
Advisor: Gregory A. Voth
2007-2011 University of Oxford
Graduate Student Researcher, Department of Biochemistry
Advisor: Mark S. P. Sansom
2006-2007 University of Bristol, UK
Undergraduate Researcher, Department of Chemistry
Advisor: Chris Willis
2005-2006 GlaxoSmithKline, UK
Industrial Placement Student

Education

2007-2011 University of Oxford
D.Phil. in Biochemistry
2003-2007 University of Bristol, UK
M.Sci. in Chemistry with Industrial Experience

Publications

  1. J. L. Baker*, N. Courtemanche*, D. L. Parton*, M. McCullagh, T. D. Pollard, G. A. Voth. Electrostatic Interactions Between the Bni1p Formin FH2 Domain and Actin Influence Actin Filament Nucleation, Structure. (2014) - in press
  2. D. L. Parton, A. Tek, M. Baaden, M. S. P. Sansom, Formation of Raft-Like Assemblies within Clusters of Influenza Hemagglutinin Observed by MD Simulations, PLoS Comp. Biol. (2013) 9:e1003034. Link
  3. J. M. Crowet, D. L. Parton, B. Hall, S. Steinhauer, R. Brasseur, L. Lins, M. S. P. Sansom, Multiscale Simulation of the Simian Immunodeficiency Virus Fusion Peptide, J. Phys. Chem. B. (2012) 116:13713. Link
  4. D. L. Parton, E. V. Akhmatskaya, M. S. P. Sansom, Multiscale Simulations of the Antimicrobial Peptide Maculatin 1.1: Water Permeation through Disordered Aggregates, J. Phys. Chem. B. (2012) 116:8485. Link
  5. D. L. Parton*, J. W. Klingelhoefer*, M. S. P. Sansom, Aggregation of model membrane proteins, modulated by hydrophobic mismatch, membrane curvature and protein class, Biophys. J. (2011) 101:691-699. Link
  6. P. A. Procopiou, C. Browning, J. M. Buckley, K. L. Clark, L. Fechner, P. M. Gore, A. P. Hancock, S. T. Hodgson, D. S. Holmes, M. Kranz, B. E. Looker, K. M. Morriss, D. L. Parton, L. J. Russell, R. J. Slack, S. L. Sollis, S. Vile, C. J. Watts, The Discovery of Phthalazinone-Based Human H(1) and H(3) Single-Ligand Antagonists Suitable for Intranasal Administration for the Treatment of Allergic Rhinitis, J. Med. Chem. (2011) 54:2183-2195. Link
  7. P. J. Bond, D. L. Parton, J. F. Clark, M. S. P. Sansom, Coarse-Grained Simulations of the Membrane-Active Antimicrobial Peptide Maculatin 1.1, Biophys. J. (2008) 95:3802-3815. Link
* Authors contributed equally

Manuscripts in Preparation or Review

  1. T. Reddy, D. Shorthouse, D. L. Parton, E. Jeffreys, P. W. Folwer, M. Chavent, M. Baaden, M. S. P. Sansom. Coarse-Grained Simulations of a Full-Scale Computational Model of the Human Influenza Virion, (2014) - submitted
  2. D. L. Parton, J. D. Chodera (2014) - three manuscripts in preparation

Awards and Scholarships

2014 Attended Hacker School - a 3 month programming retreat
2012 Full financial support for attendance at PASI Workshop at Institut Pasteur de Montevideo, Uruguay
2011-2012 Research on simulations of influenza virus featured in French national scientific magazine, La Recherche, in Oxford biochemistry magazine, Phenotype, and on the MRC BPoD website (link).
2010 HPC-Europa2 award, providing funding for a 6-week placement based in the group of Dr Marc Baaden (Institut de Biologie Physico-Chimique, Paris, France)
2010 GSK Award for poster at Oxford Department of Biochemistry Annual Retreat
2007-2011 Joint CASE Award Studentship from the BBSRC and Fujitsu Laboratories of Europe
2003 Final-year prize for Physics from Chesham High School

Teaching

2009 Demonstrator for a workshop on MD simulations and visualization for high-school students, organized by the Sutton Trust Programme, at University of Oxford
2008-2009 Tutor in Organic Chemistry, Christ Church College, University of Oxford

Peer Review

  1. Biochemistry
  2. Central European Journal of Mathematics

Selected Talks

2013 (invited) Department of Chemistry, University of Cambridge, UK
2012 (invited) Institut de Biologie Physico-Chimique, Paris, France
2009 CCPB Conference on Biomolecular Simulation, York, UK
In additional to the above, I have presented a large number of seminars and posters at a wide range of national and international scientific conferences.